Abstract Background Greater epidemiologic understanding of the relationships among fetal-infant mortality and its prognostic factors, including birthweight, could have vast public health implications.A key step toward that understanding is a realistic and tractable framework for analyzing birthweight distributions and fetal-infant mortality.The pre
Analysis of pharmacogenetic traits in two distinct South African populations
Abstract Our knowledge of pharmacogenetic variability in diverse populations is scarce, especially in sub-Saharan Africa.To bridge this gap in knowledge, Orange Sweet we characterised population frequencies of clinically relevant pharmacogenetic traits in two distinct South African population groups.We genotyped 211 tagging single nucleotide polymo
Patterns of genomic variation in the poplar rust fungus Melampsora larici-populina identify pathogenesis-related factors
Melampsora larici-populina is a fungal pathogen responsible for foliar rust disease on poplar trees, which causes damage to forest plantations worldwide, particularly in Northern Europe.The reference genome of the isolate 98AG31 was previously sequenced using a whole genome shotgun Aftermarket Parts strategy, revealing a large genome of 101 megabas
Online Power Management with Embedded Offline-Optimized Parameters for a Three-Source Hybrid Powertrain with an Experimental Emulation Application
Real-time power management in the presence of one or more reversible energy storage systems is a current issue with hybrid electric vehicles (HEVs).To evaluate the potentials of rule-based power management, optimization with respect to Poster/Canvas two conflicting objectives, fuel consumption and state of charge (SoC) deviation, is considered in t
Rapamycin Reduces Podocyte Apoptosis and is Involved in Autophagy and mTOR/ P70S6K/4EBP1 Signaling
Background/Aims: The purpose of this study was to investigate the impact of rapamycin (RAP) on autophagy in podocytes and the therapeutic effects of RAP on idiopathic membranous nephropathy (IMN).Methods: We established an in vitro model of IMN by preconditioning mouse podocytes with puromycin aminonucleoside (PAN).A Cell Counting Kit-8 was used to